Based on cyclic physiologic animal bioimpedance and body temperature a new method is being evaluated to predict estrus in dairy cattle with the aim of improving artificial insemination efficiency. Preceding in-vivo tests are being performed with a dedicated system based on the impedance converter AD5933, and a two-electrode configuration bioimplantable capsule. Acquired results will allow the optimal design of an implantable and autonomous low-power system. The implantable microsystem is being designed and simulated employing low-power techniques in a 0.35 mu m CMOS standard process.