Published in

Wiley, Animal Genetics, 2010

DOI: 10.1111/j.1365-2052.2010.02021.x

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East Friesian sheep carry aMyostatinallele known to cause muscle hypertrophy in other breeds

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This paper is available in a repository.

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Abstract

The East Friesian breed of sheep was developed in northern Germany and the Netherlands, and has become one of the worlds most productive dairy sheep. It is likely to have contributed to the foundation of other breeds, such as the Texel, which originated in the Netherlands chain of West Friesian islands. The Texel is a meat breed that displays a muscle hypertrophy phenotype caused by a G to A substitution (g.+6723G>A) in the Myostatin gene. Given the likelihood of a common population history linking Texel and East Frisian, we sought to determine if the latter also carries the mutant g.+6723A Myostatin allele despite the divergent production profiles of the two breeds.