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Instituto Oswaldo Cruz, Ministério da Saúde, Memórias do Instituto Oswaldo Cruz., suppl 1(99), p. 97-98, 2004

DOI: 10.1590/s0074-02762004000900017

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Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni

Journal article published in 2004 by Lílian Beck, Joelma R. de Souza, Daniele Sm M. Van-Lüme, Joelma R. De Souza, Clarice N. Lins de Morais, Clarice N. Lins de Morais, Wlademir G. Melo, Edeneide Xavier, Constança S. Barbosa ORCID, Marcílio L. Aroucha, Ana Lúcia C. Domingues, Tereza Favre, Otávio Pieri, Frederico Gc C. Abath, Silvia Ml L. Montenegro
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Specific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in conjunction with clinical and epidemiological data to the differential diagnosis of acute schistosomiasis.