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American Society for Clinical Investigation, Journal of Clinical Investigation, 4(99), p. 692-700

DOI: 10.1172/jci119213

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Metabolic effects of liver transplantation in cirrhotic patients.

Journal article published in 1997 by L. Luzi ORCID, G. Perseghin ORCID, E. Regalia, L. P. Sereni, A. Battezzati, D. Baratti ORCID, E. Bianchi, I. Terruzzi, H. Hilden, L. C. Groop, A. Pulvirenti, M.-R. Taskinen, L. Gennari, V. Mazzaferro
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

To assess whether liver transplantation (LTx) can correct the metabolic alterations of chronic liver disease, 14 patients (LTx-5) were studied 5+/-1 mo after LTx, 9 patients (LTx-13) 13+/-1 mo after LTx, and 10 patients (LTx-26) 26+/-2 months after LTx. Subjects with chronic uveitis (CU) and healthy volunteers (CON) were also studied. Basal plasma leucine and branched-chain amino acids were reduced in LTx-5, LTx-13, and LTx-26 when compared with CU and CON (P