Published in
PAGEpress, Reumatismo, 3(65)
DOI: 10.4081/reumatismo.2013.113
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Regional differences of vitamin D deficiency in rheumatoid arthritis patients in Italy.
,
G. D'Avola,
S. Silveri,
M. Muratore,
G. Bagnato,
N. Malavolta,
E. Cacace,
F. Silveri,
M. Caminiti,
G. Bianchi,
F. Cantatore,
B. Frediani,
A. Del Puente,
G. Minisola,
O. Di Munno
and other authors.
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Abstract
Vitamin D deficiency is very common in patients with rheumatoid arthritis (RA). Aim of this study was to evaluate the prevalence of vitamin D deficiency among the different Italian regions and whether these variations are associated with different severity of the disease. The study includes 581 consecutive RA patients (464 women), not taking vitamin D supplements, from 22 Italian rheumatology centres uniformly distributed across Italy. Together with parameters of disease activity (disease activity score 28), functional impairment (activities of daily living and health assessment questionnaire disability index) and mean sun exposure time, all patients had serum 25-hydroxyvitamin D (25OHD) measured in a centralized laboratory. Vitamin D deficiency (25OHD level