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Protein Structure Prediction, p. 43-57

DOI: 10.1007/978-1-59745-574-9_2

Protein Structure Prediction, Second Edition, p. 43-58

DOI: 10.1385/1-59745-574-1:43

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The assessment of methods for protein structure prediction

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Methods for protein structure prediction are flourishing and becoming widely available to both experimentalists and computational biologists. But, how good are they? What is their range of applicability and how can we know which method is better suited for the task at hand? These are the questions that this chapter tries to address, by describing automatic evaluation methods as well as the world-wide Critical Assessment of Techniques for Protein Structure Prediction (CASP) initiative and focusing on the specific problems of assessing the quality of a protein 3D model.