Published in
Elsevier, Growth Hormone and IGF Research, 3(19), p. 212-218, 2009
DOI: 10.1016/j.ghir.2008.09.003
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Growth hormone promotes proliferation of adult neurosphere cultures
Journal article published in 2009 by
S. McLenachan,
M. G. Lu,
M.-G. Lum,
M. J. Waters,
A. M. Turnley 
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Abstract
Growth hormone (GH) and its receptor (GHR) are widely expressed int he CNS. During development, GH signaling regulates both proliferation of neural progenitor cells as well as their differentiation into neurons and glia. Here we have examined the effect of GH signaling on adult subventricular zone derived neural progenitor cells cultured as neurospheres.