Dissemin is shutting down on January 1st, 2025

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Nature Research, Nature Biotechnology, 6(32), p. 545-550, 2014

DOI: 10.1038/nbt.2891

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The Synthetic Biology Open Language (SBOL) provides a community standard for communicating designs in synthetic biology

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The re-use of previously validated designs is critical to the evolution of synthetic biology from a research discipline to an engineering practice. Here we describe the Synthetic Biology Open Language (SBOL), a proposed data standard for exchanging designs within the synthetic biology community. SBOL represents synthetic biology designs in a community-driven, formalized format for exchange between software tools, research groups and commercial service providers. The SBOL Developers Group has implemented SBOL as an XML/RDF serialization and provides software libraries and specification documentation to help developers implement SBOL in their own software. We describe early successes, including a demonstration of the utility of SBOL for information exchange between several different software tools and repositories from both academic and industrial partners. As a community-driven standard, SBOL will be updated as synthetic biology evolves to provide specific capabilities for different aspects of the synthetic biology workflow.