Published in
Nature Research, Nature Genetics, 11(40), p. 1282-1284, 2008
DOI: 10.1038/ng.255
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Male-pattern baldness susceptibility locus at 20p11
Journal article published in 2008 by
J. Brent Richards,
J. Brent Richards,
Xin Yuan,
Frank Geller,
Dawn Waterworth,
Veronique Bataille,
Daniel Glass,
Kijoung Song,
Gerard Waeber,
Peter Vollenweider,
Katja K. H. Aben 
,
Lambertus A. L. M. Kiemeney,
Bragi Walters,
Nicole Soranzo,
Unnur Thorsteinsdottir
and other authors.
,
Lambertus A. L. M. Kiemeney,
Bragi Walters,
Nicole Soranzo,
Unnur Thorsteinsdottir
and other authors.
This paper is made freely available by the publisher.
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Abstract
We conducted a genome-wide association study for androgenic alopecia in 1,125 men and identified a newly associated locus at chromosome 20p11.22, confirmed in three independent cohorts (n = 1,650; OR = 1.60, P = 1.1 x 10(-14) for rs1160312). The one man in seven who harbors risk alleles at both 20p11.22 and AR (encoding the androgen receptor) has a sevenfold-increased odds of androgenic alopecia (OR = 7.12, P = 3.7 x 10(-15)).