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American Association for Cancer Research, Cancer Discovery, 1(4), p. 19-21, 2014

DOI: 10.1158/2159-8290.cd-13-0906

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Climbing RAS, the Everest of Oncogenes.

Journal article published in 2014 by Mariangela Russo ORCID, Federica Di Nicolantonio, Alberto Bardelli
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Summary: Mutations that activate the small GTP-binding protein KRAS are the most common oncogenic event in human tumors. Thirty years after its discovery, mutant KRAS has yet to be therapeutically conquered. Cancer Discov; 4(1); 19–21. ©2014 AACR. See related article by Faber et al., p. 42