Published in

American Urological Association (AUA), The Journal of Urology, 1(193), p. 281-285, 2015

DOI: 10.1016/j.juro.2014.07.089

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Donation After Cardiac Death Pediatric En-Bloc Renal Transplantation.

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

PURPOSE: The use of small pediatric kidneys obtained from very young donors after cardiac death (DCD) has been limited and this remains an underutilized organ source. MATERIALS AND METHODS: We reviewed all renal transplants at our institution from 2000 to 2013 to identify recipients of an en-bloc pair of kidneys from pediatric donors less than 4 years of age. The outcomes of DCD en-bloc allografts were compared with neurologic determination of death (NDD) en-bloc allografts. RESULTS: 21 recipients of en bloc renal allografts were identified of which 4 organ pairs were obtained through DCD. The mean donor age was 20.6 ± 11.6 months and mean donor weight was 12.4 ± 3.7 kg. Delayed graft function (DGF) occurred in 2/4 DCD and 3/17 NDD en bloc recipients. At one year post-transplantation, mean glomerular filtration rates (GFRs) were similar at 80.7 ± 15.3 versus 85.7 ± 33.4 mL/min/1.73 m2 in the DCD and NDD groups respectively (p = NS). Surgical complications occurred in three patients; no grafts were lost to thrombosis. CONCLUSIONS: We are encouraged to report successful transplantation of a small cohort of DCD pediatric en-bloc kidneys from donors less than 4 years of age. Outcomes at one year are comparable to NDD en bloc allograft recipients.