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BMJ Publishing Group, Gut, 9(54), p. 1232-1236, 2005

DOI: 10.1136/gut.2004.060228

Elsevier, Year Book of Gastroenterology, (2006), p. 149-150

DOI: 10.1016/s0739-5930(08)70349-0

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Anti-Saccharomyces cerevisiae and antineutrophil cytoplasmic antibodies as predictors of inflammatory bowel disease

Journal article published in 2005 by A. Wiik, Y. Shoenfeld, G. R. Lichtenstein, I. Grotto, B. Gilburd, R. D. Balicer ORCID, E. Israeli, E. Goldin
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Background and aims: Several antibodies have been reported in the sera of patients with Crohn’s disease (CD) and ulcerative colitis (UC). The most commonly described are anti-Saccharomyces cerevisiae mannan antibodies (ASCA) in CD and perinuclear antineutrophil cytoplasm antibodies (pANCA) in UC. Familial clustering of these antibodies has been described, suggesting they might be genetic markers. Our aim was to investigate the presence of these antibodies before the emergence of overt clinical manifestations.