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BMJ Publishing Group, Gut, 4(54), p. 479-487, 2005

DOI: 10.1136/gut.2004.044370

Elsevier, Year Book of Gastroenterology, (2006), p. 160-161

DOI: 10.1016/s0739-5930(08)70357-x

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The RANKL/OPG system is activated in inflammatory bowel disease and relates to the state of bone loss

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Background and aims: A substantial proportion of patients with inflammatory bowel disease (IBD) develops osteopenia and osteoporosis in the course of disease. Recent data from a mouse model of colitis suggest that the receptor activator of nuclear factor kappa B (RANKL)/osteoprotegerin (OPG) system may be responsible for bone loss.