BMJ Publishing Group, Gut, 4(54), p. 479-487, 2005
Elsevier, Year Book of Gastroenterology, (2006), p. 160-161
DOI: 10.1016/s0739-5930(08)70357-x
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Background and aims: A substantial proportion of patients with inflammatory bowel disease (IBD) develops osteopenia and osteoporosis in the course of disease. Recent data from a mouse model of colitis suggest that the receptor activator of nuclear factor kappa B (RANKL)/osteoprotegerin (OPG) system may be responsible for bone loss.