Elsevier, Urologic Oncology: Seminars and Original Investigations, 5(31), p. 549-556
DOI: 10.1016/j.urolonc.2011.03.008
Full text: Unavailable
OBJECTIVES: To analyze the predictive value of PSA for progression and the role of testosterone for quality of life (QOL) in patients with androgen deprivation therapy (ADT) for metastatic prostate cancer. MATERIALS AND METHODS: PSA and testosterone data were used from a phase III trial randomizing patients without progression and PSA /=500 ng/ml was 25%, 55%, and 76% (P = 0.03) in CAD, and 38%, 64%, and 85% (P = 0.006) in IAD, respectively. The 2-year risk of progression for PSA nadir = 0.2 ng/ml, and > 0.2 to 4 ng/ml in CAD was 31% and 70% (P