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Elsevier, Tetrahedron: Asymmetry, 10(19), p. 1200-1203

DOI: 10.1016/j.tetasy.2008.04.031

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A new approach for the asymmetric synthesis of (2S,3S)-3-hydroxypipecolic acid

Journal article published in 2008 by Liang-Xian Liu, 黄培强, Qi-Long Peng, Pei-Qiang Huang ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

An efficient stereoselective synthesis of (2S,3S)-3-hydroxypipecolic acid was achieved from (S)-glutamic acid via the furylation of an N-protected 6-hydroxy-2-piperidinone using furan as a nucleophile and the oxidation of the furyl group to a carboxylic group as the key steps. (C) 2008 Elsevier Ltd. All rights reserved.