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MDPI, International Journal of Molecular Sciences, 11(9), p. 2169-2183, 2008

DOI: 10.3390/ijms9112169

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Survey of Slaughtered Pigs for Occurrence of Ochratoxin A and Porcine Nephropathy in Serbia

Journal article published in 2008 by Dragan Milićević ORCID, Srdan Stefanović, Srđan Stefanović, Verica Jurić, An Stefanović, Milijan Jovanović, Saša Janković
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Samples of blood, kidney and liver were randomly selected from slaughtered pigs (n=90) and analyzed for ochratoxin A by HPLC. In addition, in order to obtain information on the occurrence of nephropathy, histological examinations were carried out. Of the 90 liver samples, 26.6% contained OTA in the range of 0.22–14.5 ng/g. The incidence of OTA in serum and kidney were very similar (31%, 33.3%), with a maximum concentration of 220.8 ng/mL, and 52.5 ng/g, respectively. Histopathological examination of kidneys confirmed tubulopathies with edema and cell vacuolization. In addition, hemorrhages and necrosis of proximal kidney tubules’ cells were found.