Published in

Institute of Electrical and Electronics Engineers, IEEE Transactions on Biomedical Engineering, 2(61), p. 264-272, 2014

DOI: 10.1109/tbme.2013.2282402

Links

Tools

Export citation

Search in Google Scholar

Amorphous regions-of-interest projection method for simplified longitudinal comparison of dynamic regions in cancer imaging

This paper is available in a repository.
This paper is available in a repository.

Full text: Download

Green circle
Preprint: archiving allowed
Green circle
Postprint: archiving allowed
Red circle
Published version: archiving forbidden
Data provided by SHERPA/RoMEO

Abstract

Tumors are typically analyzed as a single unit, despite their biologically heterogeneous nature. This limits correlations that can be drawn between regional variation and treatment outcome. Furthermore, despite the availability of high resolution 3D medical imaging techniques, local outcomes, (e.g. tumor growth), are not easily measured. This paper proposes a method that uses streamlines to divide a 3D region of interest (e.g. tumor) into units where local properties can be measured over the paths of growth. Parameters such as directional length and mean intensity can be measured locally at sequential time points and then compared. The method is evaluated on synthetic objects, simulated tumors, and medical images of brain tumors. The evaluations suggest that the method is suitable for mapping amorphous dynamic objects.