Dissemin is shutting down on January 1st, 2025

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Elsevier, The Lancet Oncology, 7(11), p. 646-652

DOI: 10.1016/s1470-2045(10)70104-2

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Size of sentinel-node metastasis and chances of non-sentinel-node involvement and survival in early stage vulvar cancer: results from GROINSS-V, a multicentre observational study.

Journal article published in 2010 by Maaike H. Oonk, Bettien M. van Hemel, Harry Hollema, Joanne A. de Hullu, B. M. van Hemel, Anca C. Ansink, Ignace Vergote, J. A. de Hullu, René H. Verheijen, Angelo Maggioni, Eleonora B. van Dorst, Katja N. Gaarenstroom ORCID, Peter J. Baldwin, Jacobus van der Velden, E. B. van Dorst and other authors.
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

BACKGROUND: Currently, all patients with vulvar cancer with a positive sentinel node undergo inguinofemoral lymphadenectomy, irrespective of the size of sentinel-node metastases. Our study aimed to assess the association between size of sentinel-node metastasis and risk of metastases in non-sentinel nodes, and risk of disease-specific survival in early stage vulvar cancer. METHODS: In the GROningen INternational Study on Sentinel nodes in Vulvar cancer (GROINSS-V), sentinel-node detection was done in patients with T1-T2 (