Published in
Elsevier, Microbes and Infection, 11(14), p. 881-893
DOI: 10.1016/j.micinf.2012.03.004
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Pattern recognition receptors in infectious skin diseases
Journal article published in 2012 by
H. D. de Koning,
Heleen D. de Koning,
Anna Simon,
Patrick L. J. M. Zeeuwen 
,
Joost Schalkwijk
,
Joost Schalkwijk
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Abstract
During the last decade, multiple pattern recognition receptors (PRRs) have been identified. These are involved in the innate immune response against a plethora of pathogens. However, PRR functioning can also be detrimental, even during infections. This review discusses the current knowledge on PRRs that recognize dermatotropic pathogens, and potential therapeutical implications.