Agr Interference between Clinical Staphylococcus aureus Strains in an Insect Model of Virulence

Fleming, Vicki; Feil, Ed; Sewell, Andrew K.; Day, Nicholas; Buckling, Angus; Massey, Ruth C.

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Agr Interference between Clinical Staphylococcus aureus Strains in an Insect Model of Virulence

Journal article published in 2006 by Vicki Fleming, Ed Feil, Andrew K. Sewell

, Nicholas Day, Angus Buckling, Ruth C. Massey

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Abstract

Repression of virulence by Staphylococcus aureus strains from different Agr groups has been demonstrated in vitro and is proposed as a means of competitive interference. Here, using the insect Manduca sexta, we show for the first time that this interference also occurs in vivo within a mixed population.