Metabolic control by means of insulin in patients with type 2 diabetes and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity--secondary publication

Gustafsson, I.; Malmberg, K.; Rydén, L.; Wedel, H.; Birkeland, K.; Bootsma, M.; Dickstein, K.; Efendic, S.; Fisher, M.; Hamsten, A.; Herlitz, Johan; Hildebrandt, Pr; MacLeod, K.; Laakso, M.; Torp-Pedersen, Ct; Waldentrom, A.

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Metabolic control by means of insulin in patients with type 2 diabetes and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity--secondary publication

Published in 2006 by I. Gustafsson, K. Malmberg, L. Rydén, H. Wedel, K. Birkeland, M. Bootsma, K. Dickstein, S. Efendic, M. Fisher, A. Hamsten, Johan Herlitz, Pr Hildebrandt, K. MacLeod, M. Laakso, Ct Torp-Pedersen and other authors.

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Abstract

Patients with diabetes have an unfavourable prognosis after an acute myocardial infarction. The DIGAMI 2 study investigated the effect of various metabolic treatment strategies in type 2 diabetic patients with acute myocardial infarction: acutely introduced, long-term insulin treatment did not improve survival when compared with conventional management at similar levels of glucose control. However, good glucose control seems important since the glucose level was found to be a strong predictor of long-term mortality in this patient category.