Dissemin is shutting down on January 1st, 2025

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Nature Research, Nature Methods, 1(11), p. 47-50, 2013

DOI: 10.1038/nmeth.2734

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A quantitative liposome microarray to systematically characterize protein-lipid interactions

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Lipids have a role in virtually all biological processes, acting as structural elements, scaffolds and signaling molecules, but they are still largely under-represented in known biological networks. Here we describe a liposome microarray-based assay (LiMA), a method that measures protein recruitment to membranes in a quantitative, automated, multiplexed and high-throughput manner.