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Elsevier, Veterinary Anaesthesia and Analgesia, 6(38), p. 544-554, 2011

DOI: 10.1111/j.1467-2995.2011.00659.x

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Effects of a constant rate infusion of detomidine on cardiovascular function, isoflurane requirements and recovery quality in horses

Journal article published in 2011 by Stijn Schauvliege ORCID, Miguel Gozalo Marcilla, Kirsten Verryken, Luc Duchateau, Lindsey Devisscher ORCID, Frank Gasthuys
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Objective To examine the influence of a detomidine constant rate infusion (CRI) on cardiovascular function, isoflurane requirements and recovery quality in horses undergoing elective surgery. Study design Prospective, randomized, blinded, clinical trial. Animals Twenty adult healthy horses. Methods After sedation (detomidine, 10 mu g kg(-1) intravenously [IV]) and induction of anaesthesia (midazolam 0.06 mg kg(-1), ketamine 2.2 mg kg(-1) IV), anaesthesia was maintained with isoflurane in oxygen/air (inspiratory oxygen fraction 55%). When indicated, the lungs were mechanically ventilated. Dobutamine was administered when MAP