Published in
Oxford University Press, The Journal of Clinical Endocrinology & Metabolism, 11(94), p. 4398-4405, 2009
DOI: 10.1210/jc.2009-1082
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Glucagon-like peptide-1 receptor imaging for localization of insulinomas
Journal article published in 2009 by
Emanuel Christ 
,
Damian Wild,
Flavio Forrer,
Michael Brändle,
Rahel Sahli,
Thomas Clerici,
Beat Gloor,
Ferdinand Martius,
Helmut Maecke,
Jean Claude Reubi
,
Damian Wild,
Flavio Forrer,
Michael Brändle,
Rahel Sahli,
Thomas Clerici,
Beat Gloor,
Ferdinand Martius,
Helmut Maecke,
Jean Claude Reubi
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Abstract
The surgical removal of insulinomas is hampered by difficulties to localize it using conventional radiological procedures. Recently these tumors were shown to exhibit a very high density of glucagon-like peptide-1 receptors (GLP-1R) in vitro that may be used as specific targets for in vivo receptor radiolabeling.