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Elsevier, Psychiatry Research, 2-3(200), p. 1018-1021

DOI: 10.1016/j.psychres.2012.04.030

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Gene expression of peripheral blood lymphocytes may discriminate patients with schizophrenia from controls

Journal article published in 2012 by Mariana Maschietto, Paulo Belmonte de-Abreu, Aderbal R. Silva, Renato D. Puga, Leandro Lima, Carlos B. Pereira, Eduardo Y. Nakano, Barbara Mello, Clarissa S. Gama, Paulo Belmonte-De-Abreu, Dirce M. Carraro, Joana Almeida Palha ORCID, Helena Brentani
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This paper is available in a repository.

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Abstract

To identify a classifier in schizophrenia, blood gene expression profiling was applied to patients with schizophrenia under different treatments and to controls. Expression of six genes discriminated patients with sensitivity of 89.3% and specificity of 90%, supporting the use of peripheral blood as biological material for diagnosis in schizophrenia.