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Elsevier, Free Radical Biology and Medicine, 5(24), p. 778-788

DOI: 10.1016/s0891-5849(97)00357-2

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Mechanisms of Asbestos-induced Nitric Oxide Production by Rat Alveolar Macrophages in Inhalation and in vitro Models 11Supported by grants from NHLBI (RO1 HL39469) and NIEHS (RO1 03878).

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

To evaluate the contribution of reactive nitrogen species to inflammation by asbestos, Fischer 344 rats were exposed to crocidolite or chrysotile asbestos by inhalation to determine whether increases occurred in nitric oxide (NO·) metabolites from alveolar macrophages (AMs). AMs from animals inhaling asbestos showed significant elevations ( p