Elsevier, Free Radical Biology and Medicine, 5(24), p. 778-788
DOI: 10.1016/s0891-5849(97)00357-2
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To evaluate the contribution of reactive nitrogen species to inflammation by asbestos, Fischer 344 rats were exposed to crocidolite or chrysotile asbestos by inhalation to determine whether increases occurred in nitric oxide (NO·) metabolites from alveolar macrophages (AMs). AMs from animals inhaling asbestos showed significant elevations ( p