Published in
Wiley, Journal of the Science of Food and Agriculture, 1(90), p. 65-69, 2009
DOI: 10.1002/jsfa.3780
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Bile salt deconjugation and cholesterol removal from media by Lactobacillus strains used as probiotics in chickens
,
Norhani A. P. Abdullah,
Clemente Michael Vui Ling Wong,
Chinna Karuthan,
Yin Wan Ho
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Abstract
BACKGROUND: Bile salt deconjugation by Lactobacillus strains is often closely linked to bile tolerance and survival of the strains in the gut and lowering of cholesterol in the host. The present study investigated the deconjugation of bile salts and removal of cholesterol by 12 Lactobacillus strains in vitro. The 12 strains were previously isolated from the gastrointestineal tract of chickens. RESULTS: The 12 Lactobacillus strains could deconjugate sodium glycocholate (GCA, 16.87-100%) and sodium taurocholate (TCA, 1.69-57.43%) bile salts to varying degrees, with all strains except L. salivarius I 24 having a higher affinity for GCA. The 12 Lactobacillus strains also showed significant (P