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Elsevier, Journal of Affective Disorders, (166), p. 48-58

DOI: 10.1016/j.jad.2014.04.078

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Efficacy and tolerability of antidepressants for sub-threshold depression and for mild major depressive disorder

Journal article published in 2014 by Isobel M. Cameron, Ian C. Reid, Steve A. Macgillivray ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Background It is commonly assumed that robust evidence exists for the lack of efficacy of antidepressants at the milder end of the depression severity spectrum. In light of specific limitations of existing reviews, we assess if antidepressants are efficacious and tolerable for sub-threshold or mild major depressive disorder (MDD). Method Systematic review and meta-analysis of randomised controlled trials of adults with sub-threshold depression or mild MDD initial baseline symptom severity of HRSD © 2014 Elsevier B.V. All rights reserved.