Published in
Elsevier, Journal of Biological Chemistry, 27(287), p. 23068-23078, 2012
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- [www.ncbi.nlm.nih.gov] | PDF
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Interplay between T Cell Receptor Binding Kinetics and the Level of Cognate Peptide Presented by Major Histocompatibility Complexes Governs CD8 + T Cell Responsiveness
Journal article published in 2012 by
Melita Irving 
,
Vincent Zoete,
Michael Hebeisen,
Daphné Schmid,
Petra Baumgartner,
Philippe Guillaume,
Pedro Romero,
Daniel Speiser,
Immanuel Luescher,
Nathalie Rufer,
Olivier Michielin
,
Vincent Zoete,
Michael Hebeisen,
Daphné Schmid,
Petra Baumgartner,
Philippe Guillaume,
Pedro Romero,
Daniel Speiser,
Immanuel Luescher,
Nathalie Rufer,
Olivier Michielin
This paper is made freely available by the publisher.
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Abstract
Background: Adaptive immunity requires T cell receptor (TCR) recognition of antigenic peptide in complex with major histocompatibility complexes (pMHC).