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American Society of Nephrology, Clinical Journal of the American Society of Nephrology, 6(2), p. 1131-1139, 2007

DOI: 10.2215/cjn.04371206

Elsevier, Year Book of Medicine, (2008), p. 229-231

DOI: 10.1016/s0084-3873(08)79129-6

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Effect of Intensive Lipid Lowering with Atorvastatin on Renal Function in Patients with Coronary Heart Disease

Journal article published in 2007 by James Shepherd, John J. P. Kastelein, Vera Bittner ORCID, Prakash Deedwania, Andrei Breazna, Stephen Dobson, Daniel J. Wilson, Andrea Zuckerman, Nanette K. Wenger
This paper is available in a repository.
This paper is available in a repository.

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Abstract

BACKGROUND AND OBJECTIVES: Data suggest that atorvastatin may be nephroprotective. This subanalysis of the Treating to New Targets study investigated how intensive lipid lowering with 80 mg of atorvastatin affects renal function when compared with 10 mg in patients with coronary heart disease. DESIGN, SETTING, PARTICIPANTS, ; MEASUREMENTS: A total of 10,001 patients with coronary heart disease and LDL cholesterol levels of or = 60 ml/min per 1.73 m2 in significantly more patients and declined to