The deformation-dependent mass Kratzer model is constructed by considering the Kratzer potential in a Bohr Hamiltonian, in which the mass is allowed to depend on the nuclear deformation, and solving it by using techniques of supersymmetric quantum mechanics (SUSYQM), involving a deformed shape invariance condition. Analytical expressions for spectra and wave functions are derived for separable potentials in the cases of γ-unstable nuclei, axially symmetric prolate deformed nuclei, and triaxial nuclei, implementing the usual approximations in each case. Spectra and B(E2) transition rates are compared to experimental data. The dependence of the mass on the deformation, dictated by SUSYQM for the potential used, moderates the increase of the moment of inertia with deformation, removing a main drawback of the model. © 2013 American Physical Society. ; SCOPUS: ar.j ; info:eu-repo/semantics/published