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American Chemical Society, The Journal of Physical Chemistry A, 37(116), p. 9321-9330, 2012

DOI: 10.1021/jp307928a

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Excited-State Dynamics of Bis-dehydroxycurcumin Carboxylic Acid, a Water-Soluble Derivative of the Photosensitizer Curcumin

Journal article published in 2012 by Luca Nardo, Angelo Maspero, Marco Selva, Maria Bondani, Giovanni Palmisano ORCID, Erika Ferrari, Monica Saladini
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Bis-dehydroxycurcumin carboxylic acid (K2A23) is a synthetic curcuminoid designed to exhibit enhanced water solubility and photosensitizing potential with respect to natural curcumin. In this work, the tendency of the compound to form intra- and intermolecular hydrogen bonds in the ground state is studied by UV-visible absorption and by nuclear magnetic resonance (NMR). The excited-state dynamics of the drug are probed in different environments by means of time-correlated single-photon counting measurements and related to its hydrogen bonding affinity in the excited state.