Elsevier, Nuclear Medicine and Biology, 6(40), p. 831-840
DOI: 10.1016/j.nucmedbio.2013.05.004
Full text: Unavailable
The prognosis of malignant gliomas remains largely unsatisfactory for the intrinsic characteristics of the pathology and for the delayed diagnosis. Multimodal imaging based on PET and MRI may assess the dynamics of disease onset and progression allowing the validation of preclinical models of glioblastoma multiforme (GBM). The aim of this study was the characterization of a syngeneic rat model of GBM using combined in vivo imaging and immunohistochemistry.