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Lippincott, Williams & Wilkins, Transplantation, 12(89), p. 1471-1475, 2010

DOI: 10.1097/tp.0b013e3181dc13e7

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C4d-fixing capability of low-level donor-specific HLA antibodies is not predictive for early antibody-mediated rejection

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Recent studies indicate that not all low-level donor-specific human leukocyte antigen (HLA) antibodies (HLA-DSA) (i.e., positive by solid-phase assays, negative by complement-dependent cytotoxic-crossmatch) have a detrimental clinical impact. The aim of this study was to investigate whether the pretransplant C4d-fixing capability allows distinguishing harmful from presumably clinically irrelevant HLA-DSA.