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Elsevier, Tetrahedron Letters, 26(50), p. 3702-3705, 2009

DOI: 10.1016/j.tetlet.2009.03.213

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The first unique synthetic mycobacterial cord factors

Journal article published in 2009 by Juma’a R. Al Dulayymi, Seppe Vander Beken, Al Dulayymi, Mark S. Baird ORCID, Maximiliano Maza-Iglesias, Seppe Vander Beken, Johan Grooten
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This paper is available in a repository.

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Abstract

Synthetic mycolic acids matching the overall structure of the major alpha- and methoxy-mycolic acids of Mycobacterium tuberculosis are coupled to trehalose to generate the corresponding synthetic trehalose dimycolate (TDM; cord factor) and trehalose monomycolate (TMM). (C) 2009 Elsevier Ltd. All rights reserved.