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Elsevier, Sleep Medicine, 10(15), p. 1251-1258

DOI: 10.1016/j.sleep.2014.04.010

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Self-reported sleep duration, white blood cell counts and cytokine profiles in European adolescents: the HELENA study

Journal article published in 2014 by Fátima Pérez de Heredia, Fátima Pérez de Heredia ORCID, F. P. Heredia, Marta Garaulet, Sonia Gómez-Martínez, Ligia E. Díaz, Julia Wärnberg ORCID, S. Gomez-Martinez, Odysseas Androutsos, Nathalie Michels ORCID, Christina Breidenassel, Magdalena Cuenca-García, J. Wurnerg, Inge Huybrechts, Frederic Gottrand and other authors.
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Abstract

Background: Sleep patterns face important changes during adolescence. This can have implications for the immune system, which is regulated by the sleep–wake cycle; however, most studies relating sleep and immune system have been conducted on adults. Objective: To study the relationships between sleep duration, immune cell counts, and cytokines in Eu- ropean adolescents participating in the HELENA Cross-Sectional Study. Methods: Adolescents(12.5–17.5years;n=933;53.9%girls)weregroupedaccordingtoself-reportedsleep duration into