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Oxford University Press (OUP), Briefings in Bioinformatics, 1(8), p. 45-59

DOI: 10.1093/bib/bbl014

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Agents in bioinformatics, computational and systems biology.

Journal article published in 2006 by Emanuela Merelli ORCID, Giuliano Armano, Nicola Cannata, Flavio Corradini, Mark d'Inverno, M. D'Inverno, Andreas Doms, Phillip Lord, Andrew Martin, Luciano Milanesi, Steffen Moeller, S. Mller, Steffen Möller, Michael Schroeder, Michale Luck ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The adoption of agent technologies and Multi-Agent Systems constitutes an emerging area in bioinformatics. In this paper, we report on the activity of the Working Group on Agents in Bioinformatics (BIOAGENTS) founded during the first AgentLink III Technical Forum meeting on the 2nd of July, 2004, in Rome. The meeting provided an opportunity for seeding collaborations between the agent and bioinformatics communities to develop a different (agent-based) approach of computational frameworks both for data analysis and management in bioinformatics and for systems modelling and simulation in computational and systems biology. The collaborations gave rise to applications and integrated tools that we summarize and discuss in the context of the state of the art of this area. We investigate on future challenges and argue that the field should still be explored from many perspectives ranging from bio-conceptual languages for agent-based simulation, to the definition of bio-ontology-based declarative languages to be used by information agents, and to the adoption of agents for computational Grids.