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Oxford University Press, European Heart Journal, 43(35), p. 3004-3012, 2014

DOI: 10.1093/eurheartj/ehu303

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Impact of left ventricular function in relation to procedural outcomes following percutaneous coronary intervention: insights from the British Cardiovascular Intervention Society

Journal article published in 2014 by Mamas A. Mamas, Simon G. Anderson ORCID, Peter D. O'Kane, Bernard Keavney, James Nolan, Keith G. Oldroyd, Divaka Perera, Simon Redwood, Azfar Zaman, Anderson SG O'Kane PD Keavney B Nolan J Oldroyd KG Perera D Redwood S Zaman A Ludman PF de Belder MA: on behalf of the British Cardiovascular Intervention Society and the National Institute for Cardiovascular Outcomes Research Mamas, Peter F. Ludman, Mark A. de Belder, Simon G. Anderson Peter D. O’Kane Bernard Keavney James Nolan Keith G. Oldroyd Divaka Perera Simon Redwood Azfar Zaman Peter F. Ludman and Mark A. de Belder Mamas A. Mamas
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This paper was not found in any repository, but could be made available legally by the author.

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Abstract

AIM: Between 10 and 30% of patients undergoing percutaneous coronary intervention (PCI) have left ventricular (LV) dysfunction. We investigate the association between LV function on early and late mortality outcomes in a national 'real-world' cohort undergoing PCI in the elective and acute coronary syndrome setting through analysis of the British Cardiovascular Intervention Society (BCIS) data set. METHODS AND RESULTS: The relationship between LV function and 30-day mortality in patients undergoing PCI for elective, ST-elevation myocardial infarction (STEMI) and non-ST elevation myocardial infarction (NSTEMI) indications was studied in 230 464 patients in the UK between 2006 and 2011. Abnormal LV function was an independent predictor of 30-day mortality outcomes: 30-day mortality risk for patients with moderate LV function (EF: 30-49%) (HR: 2.91; 95% CI: 2.43-3.49, P 50%). The independent prognostic impact of poor LV function on 30-day mortality increased from elective PCI (HR: 3.72: 95% CI: 2.21-6.25, P