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Elsevier, Reproductive BioMedicine Online, 1(18), p. 111-119

DOI: 10.1016/s1472-6483(10)60432-4

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Does altered oxygenation or reactive oxygen species alter cell turnover of BeWo choriocarcinoma cells?

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

This study assessed the effect of 20 and 6% ambient oxygen (O(2)) or 5-50 micromol/l hydrogen peroxide (H(2)O(2)) on apoptosis, necrosis, proliferation and fusion of BeWo cells. The expression of p53, Mdm2 and Bax was assessed by western blotting. Apoptosis was increased in cells cultured in 6% O(2) tension and 50 micromol/l H(2)O(2) (P