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Thieme Gruppe, Synlett: Accounts and Rapid Communications in Synthetic Organic Chemistry, 13(2011), p. 1845-1848, 2011

DOI: 10.1055/s-0030-1260953

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Sweet and Salted: Sugars Meet Hydroxyapatite

Distributing this paper is prohibited by the publisher
Distributing this paper is prohibited by the publisher

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Abstract

Carbonated hydroxyapatite (CHA) has been successfully biodecorated with carbohydrate derivatives, via silylation of the hydroxy groups of the apatite and subsequent covalent bonding with a suitably functionalized carbohydrate moiety. The presented procedure opens the way toward covalent biofunctionalisation of CHA with carbohydrates.