Published in
Oxford University Press (OUP), Bioinformatics, 24(26), p. 3028-3034
DOI: 10.1093/bioinformatics/btq590
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
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Discovering homotypic binding events at high spatial resolution
Journal article published in 2010 by
Yuchun Guo,
Georgios Papachristoudis,
Robert C. Altshuler 
,
Georg K. Gerber,
Tommi S. Jaakkola,
David K. Gifford,
Shaun Mahony
,
Georg K. Gerber,
Tommi S. Jaakkola,
David K. Gifford,
Shaun Mahony
This paper is made freely available by the publisher.
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Abstract
Motivation: Clusters of protein–DNA interaction events involving the same transcription factor are known to act as key components of invertebrate and mammalian promoters and enhancers. However, detecting closely spaced homotypic events from ChIP-Seq data is challenging because random variation in the ChIP fragmentation process obscures event locations.