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First defection of the equine herpesvirus 1 neuropathogenic variant in Brazil
Journal article published in 2011 by
E. Mori 
,
Alexandre Secorun Borges,
D. J. Z. Delfiol,
José Paes de Oliveira Filho,
Roberto Calderon Gonçalves,
D. Q. Cagnini,
M. C. C. S. H. Lara,
E. M. S. Cunha,
E. M. C. Villalobos ,
A. F. C. Nassar,
A. M. M. G. Castro,
P. E. Brandao,
L. J. Richtzenhain
,
Alexandre Secorun Borges,
D. J. Z. Delfiol,
José Paes de Oliveira Filho,
Roberto Calderon Gonçalves,
D. Q. Cagnini,
M. C. C. S. H. Lara,
E. M. S. Cunha,
E. M. C. Villalobos ,
A. F. C. Nassar,
A. M. M. G. Castro,
P. E. Brandao,
L. J. Richtzenhain
Abstract
This report describes the first detection of an equine herpesvirus 1 (EHV-1) neuropathogenic variant (G 2254/D 752) in Brazil from a case of fatal equine herpesvirus myeloencephalopathy (EHM) in a mare. The results of nucleotide sequencing of the EHV-1 ORF30 gene showed that two other Brazilian EHV-1 isolates from EHM cases are representatives of the non-neuropathogenic variant (A 2254/N 752), suggesting that other unidentified factors are probably also involved in the neuropathogenicity of EHV-1 in horses. These findings will contribute to the epidemiological knowledge of EHV-1 infection in Brazil.