Laminar burning velocities for methanol, ethanol, and binary and quaternary mixtures of these with iso-octane and n-heptane, have been determined using the heat flux method on a flat flame adiabatic burner. Measurements were done for an equivalence ratio range between 0.7 and 1.5 and for a range of temperatures between 298 K and 358 K at atmospheric pressure. The present study expands the available data on laminar burning velocities of alcohol–hydrocarbon blends and validates simple mixing rules for predicting the laminar burning velocity for a wider range of fuel blends of hydrocarbons with methanol and/or ethanol. It is shown that simple mixing rules that consider the energy fraction of the blend’s components are accurate enough to predict the experimentally determined laminar burning velocity of the mixtures.