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Oxford University Press, Nucleic Acids Research, suppl_2(36), p. W320-W326, 2008

DOI: 10.1093/nar/gkn292

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GeneCAT—novel webtools that combine BLAST and co-expression analyses

Journal article published in 2008 by Marek Mutwil, Jens Øbro, Jens Obro, William G. T. Willats ORCID, Staffan Persson ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The gene co-expression analysis toolbox (GeneCAT) introduces several novel microarray data analyzing tools. First, the multigene co-expression analysis, combined with co-expressed gene networks, provides a more powerful data mining technique than standard, single-gene co-expression analysis. Second, the high-throughput Map-O-Matic tool matches co-expression pattern of multiple query genes to genes present in user-defined subdatabases, and can therefore be used for gene mapping in forward genetic screens. Third, Rosetta combines co-expression analysis with BLAST and can be used to find 'true' gene orthologs in the plant model organisms Arabidopsis thaliana and Hordeum vulgare (Barley). GeneCAT is equipped with expression data for the model plant A. thaliana, and first to introduce co-expression mining tools for the monocot Barley. GeneCAT is available at http://genecat.mpg.de.