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Wiley, European Journal of Heart Failure, 6-7(9), p. 587-593, 2007

DOI: 10.1016/j.ejheart.2007.02.008

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Impact of Heart Failure and Left Ventricular Function on Long-Term Survival — Report of a Community-Based Cohort Study in Taiwan

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Background: There is little community-based information on heart failure (HF) prognosis in ethnic Chinese populations, in whom there is a low prevalence of coronary heart disease. Aims: To study the impact of HF and left ventricular function on long-term all-cause mortality. Methods and results: This community-based prospective cohort study included 2660 subjects (1215 men, 1445 women, mean age 54.4±11.9 years) over a 10 year follow-up period. The prevalence of HF was 5.5%. Hypertension was the most common factor related to HF. The five and ten year all-cause mortality was higher in the HF/preserved LVEF group (14.1% and 24.4%) and the HF/ impaired LVEF group(29.2% and 48.2%) than in the HF-free group (6.0% and 14.6%, pb0.0001 for both ). In multivariable Cox analyses, controlling for sex, LV mass, atrial fibrillation, hypertension, coronary heart disease, HF/preserved LVEF and HF/impaired LVEF were important predictors of allcause mortality ( p=0.007). Conclusions: Hypertension is a major heart failure related disease. HF and LV systolic dysfunction are associated with a significant increase in all-cause mortality in an ethnic Chinese population. ; 附設醫院急診醫學部 ; 醫學院附設醫院 ; 期刊論文