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Georg Thieme Verlag, Synlett: Accounts and Rapid Communications in Synthetic Organic Chemistry, 13(2010), p. e7-e7

DOI: 10.1055/s-0030-1258014

Georg Thieme Verlag, Synlett: Accounts and Rapid Communications in Synthetic Organic Chemistry, 13(2010), p. 1943-1946

DOI: 10.1055/s-0030-1258479

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Synthesis of Novel Haptens and Conjugates for Antibody Production against Kainoid Family

Journal article published in 2010 by [nl]Bernard Bennetau, Etienne Baco, Luc Vellutini, Jean-Paul Pillot, Bernard Bennetau, François-Xavier Felpin ORCID, Jean-Marie Schmitter, Marie Degueil
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Amnesic shellfish poisoning (ASP) is caused by consumption of contaminated seafood that has accumulated kainic acid or kainoid analogues such as domoic acid. Among the different ASP bioassays, immunoassays are an attractive alternative to the in vivo mouse bioassay. Herein, we report the synthesis and bioconjugation of two new haptens for the generation of a specific antibody against members of the kainoid family.