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Lippincott, Williams & Wilkins, Diseases of the Colon and Rectum, 10(56), p. e396-e397, 2013

DOI: 10.1097/dcr.0b013e31829f3da8

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Comments on Decision Analysis for Patients With T1 Adenocarcinoma of the Low Rectum:

Journal article published in 2013 by Massimiliano Mistrangelo, Alberto Arezzo, Mario Morino ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

We have read with great interest the article by Johnston et al,1 who suggest a decision analysis for patients with T1 adenocarcinoma of the low rectum. We believe that the article presents 2 major drawbacks. In Table 1, the authors 1 include in local excision (LE) both transanal endoscopic microsurgery (TEM) and classical transanal local excision (TLE), techniques that we do not consider comparable. International literature has demonstrated the superiority of TEM vs TLE. Moore et al 2 and de Graaf et al 3 showed that TEM was more likely to yield clear margins (90% vs 71%, p = 0.001 and 88% vs 50%, p 3 cm 8 are independent predictors of recurrence. Therefore, although we agree that LE plays a fundamental role in the modern treatment of early rectal cancer, we believe that, when LE is indicated, TEM should be the technique of choice. Furthermore, different clinical strategies should be proposed for T1sm1 compared with T1sm2/3, aside from decision analysis.