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Springer Verlag, Pediatric Radiology, 1(43), p. 55-59

DOI: 10.1007/s00247-012-2481-4

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Pediatric brain injury: Can DTI scalars predict functional outcome?

Journal article published in 2013 by Duan Xu ORCID, Pratik Mukherjee ORCID, A. James Barkovich
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Diffusion imaging has made significant inroads into the clinical diagnosis of a variety of diseases by inferring changes in microstructure, namely cell membranes, myelin sheath and other structures that inhibit water diffusion. This review discusses recent progress in the use of diffusion parameters in predicting functional outcome. Studies in the literature using only scalar parameters from diffusion measurements, such as apparent diffusion coefficient (ADC) and fractional anisotropy (FA), are summarized. Other more complex mathematical models and post-processing uses are also discussed briefly.