Published in
American Association of Pharmaceutical Scientists, AAPS PharmSciTech, 3(14), p. 1098-1100
DOI: 10.1208/s12249-013-9994-5
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Note on the Measurement of Bulk Density and Tapped Density of Powders According to the European Pharmacopeia
Journal article published in 2013 by
J. P. Sousa E. Silva 
,
J. P. Sousa e. Silva,
D. Splendor,
I. M. B. Gonçalves,
P. Costa,
J. M. Sousa Lobo
,
J. P. Sousa e. Silva,
D. Splendor,
I. M. B. Gonçalves,
P. Costa,
J. M. Sousa Lobo
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Abstract
The apparent volume and compressibility index of commonly used excipients were evaluated according to European Pharmacopeia monograph (seventh edition) in order to study the influence of the procedure conditions. The results suggested that the leveling of the powder inside the cylinder ought to be avoided.